ArticleCell reports2026
Tracing NAD
Abstract read
In one paragraph
Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A metabolic constraint in de novo NAD+ synthesis drives mucosal inflammation in IBD.Journal of Crohn's & colitis · 2026Article
- Tryptophan pathway metabotypes associate with disease activity and immune-metabolic dysfunction in inflammatory bowel disease.medRxiv : the preprint server for health sciences · 2026Article
- Systematic Screening of Tryptophan Metabolism Identifies Site- and Microbiota-Dependent Signatures of Tryptophan Utilization in Experimental Colitis.International journal of tryptophan research : IJTR · 2026Article
Corrections and comments
- Update ofTracing NAD2025
Authors and funding
18 authors.
Abrar I AlsaadiDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Lina WehkampInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Anant A PothakamuryDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Mahmoud S YahiaDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Praveena PrasadDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Clara GilloteauDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Jaedon SadlerDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Jaclyn D SmithDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Brenita C JenkinsDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Garret S DivenDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Johanna BornhäuserInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Taous MekdoudInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Shuchang TianDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Philip RosenstielInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Stefan SchreiberInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Jordan E BisanzDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA.
Konrad AdenInstitute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany; Department of Internal Medicine L., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Melanie R McReynoldsDepartment of Biochemistry and Molecular Biology, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, PA, USA. Electronic address: mcreynolds@psu.edu.
Funding
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2MDecoding Microbial Diversity in the Human Gut MicrobiomeR35GM151045 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Jordan Adam Bisanz · 2023 to 2026
$1.5MNIGMS NIH HHS R35 GM151045NIGMS NIH HHS T32 GM108563
Abstract
Host-microbiota metabolic interactions critically regulate nicotinamide adenine dinucleotide (NAD
Indexed as
CP: metabolismCP: microbiologyDSS colitisgut microbiotahost-microbiome interactionsIBDkynurenine pathwaymetabolomicsNAD(+)nicotinamidestable isotope tracingtryptophan
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.