ReviewCureus2026
Enhancing Healing in Oral Surgical Procedures: A Review on Biomaterials, Growth Factors, and Tissue Engineering.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral surgical procedures require predictable healing of mucosal, periodontal, peri-implant, and maxillofacial tissues, yet repair is often challenged by microbial exposure, inflammation, mechanical stress, systemic disease, and complex defect architecture. Although biomaterials, growth factors, platelet concentrates, stem-cell therapies, hydrogels, and three-dimensional tissue-engineered constructs have been widely investigated, their clinical translation remains inconsistent because of protocol heterogeneity, variable outcome measures, limited long-term evidence, and procedure-specific differences in healing demands. This review evaluates current regenerative strategies used to enhance healing after oral surgical procedures, with emphasis on biological mechanisms, clinical applications, comparative effectiveness, translational barriers, and future therapeutic potential. Literature published between 2018 and 2026 was identified through PubMed, Scopus, Web of Science, and Google Scholar using terms related to oral wound healing, biomaterials, growth factors, platelet concentrates, stem cells, guided bone regeneration, periodontal regeneration, implant healing, and maxillofacial reconstruction. The evidence indicates that biomaterials improve wound stability, space maintenance, clot retention, and controlled delivery, while growth factors and platelet concentrates support angiogenesis, epithelial repair, fibroblast activity, matrix deposition, and bone remodeling. Tissue-engineering approaches further expand regenerative capacity through scaffold-cell-signal systems, dental stem cells, extracellular vesicles, and three-dimensional bioprinting. Overall, integrated regenerative strategies may improve oral surgical healing, but standardized protocols, robust clinical trials, and patient-centered outcomes are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.