Evidence map›Paper›PMID 42500774›Full record

ArticleCureus2026

Severe Thrombocytopenia and Leukopenia as the Initial Manifestations of Brucella melitensis Bacteremia: A Case Report.

Carolina Pico Mendoza, Linda E Hernandez Soto, Jose F Gomez Zapata, Luisa F Vazquez Enriquez, Kenia Dominguez Romo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina Pico MendozaDepartment of Internal Medicine, Hospital General de Zona No. 33, Instituto Mexicano del Seguro Social, Monterrey, MEX.
Linda E Hernandez SotoDepartment of Internal Medicine, Hospital General de Zona No. 33, Instituto Mexicano del Seguro Social, Monterrey, MEX.
Jose F Gomez ZapataDepartment of Internal Medicine, Hospital General de Zona No. 67, Instituto Mexicano del Seguro Social, Monterrey, MEX.
Luisa F Vazquez EnriquezDepartment of Internal Medicine, Hospital General de Zona No. 33, Instituto Mexicano del Seguro Social, Monterrey, MEX.
Kenia Dominguez RomoDepartment of Internal Medicine, Hospital General de Zona No. 33, Instituto Mexicano del Seguro Social, Monterrey, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucellosis is a zoonotic infection with diverse clinical manifestations that frequently delay diagnosis because of its nonspecific presentation. Hematologic abnormalities have been described in affected patients; however, severe thrombocytopenia remains an uncommon finding. We present the case of a 50-year-old woman who was admitted with a four-day history of fever up to 39°C, diffuse abdominal pain, vomiting, and secretory diarrhea. Initial laboratory evaluation revealed leukopenia (2.7 × 10³/μL), severe thrombocytopenia (29 × 10³/μL), hyponatremia, and elevated liver enzymes. The patient remained hemodynamically stable and showed progressive clinical improvement with supportive management. As part of the etiologic workup, two independent blood cultures yielded

Indexed as

bacteremiabrucella melitensisbrucellosisleukopeniasevere thrombocytopenia

Identifiers

PMID42500774
PMCPMC13398910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.