Evidence map›Paper›PMID 42500579›Full record

ArticleOncology research2026

TGFβ Blockade by Inhibition of Enolase-1-Mediated Plasmin Targets Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma.

Mao-Lin Chen, I-Che Chung, Kevin Chih-Yang Huang, K S Clifford Chao, Ta-Tung Yuan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mao-Lin ChenDepartment of Research and Development, HuniLife Biotechnology Inc., Taipei City, Taiwan.
I-Che ChungDepartment of Research and Development, HuniLife Biotechnology Inc., Taipei City, Taiwan.
Kevin Chih-Yang HuangDepartment of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.
K S Clifford ChaoCenter of Proton Therapy, China Medical University Hospital, Taichung, Taiwan.
Ta-Tung YuanDepartment of Research and Development, HuniLife Biotechnology Inc., Taipei City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Pancreatic DuctalDNA-Binding ProteinsFibrinolysinPancreatic NeoplasmsPhosphopyruvate HydrataseTransforming Growth Factor betaTumor-Associated MacrophagesTumor Suppressor ProteinsAnimalsCell Line, TumorCell ProliferationDeoxycytidineFemaleGemcitabineHumansMaleDeoxycytidineDNA-Binding ProteinsENO1 protein, humanFibrinolysinGemcitabinePhosphopyruvate HydrataseTransforming Growth Factor betaTumor Suppressor ProteinsENO1monoclonal antibodypancreatic ductal adenocarcinomaTGFβ activationtumor-associated macrophagetumor microenvironment

Identifiers

PMID42500579
PMCPMC13397359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.