Evidence map›Paper›PMID 42500496›Full record

ArticleRadiology case reports2026

Anti leucine-rich glioma-inactivated 1 (LGI1) antibody-positive limbic encephalitis with evolving basal ganglia T1WI hyperintensity: A case report.

Ryoko Noha, Akira Yogi, Yukihiro Namihira, Mitsuyoshi Kanazawa, Yukari Tomori, Nanae Tsuchiya, Gyo Iida, Akihiro Nishie

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryoko NohaDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Akira YogiDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Yukihiro NamihiraDepartment of Neurology, Okinawa Prefectural Nanbu Medical Center & Children's Medical Center, Shimajiri, Japan.
Mitsuyoshi KanazawaDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Yukari TomoriDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Nanae TsuchiyaDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Gyo IidaDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.
Akihiro NishieDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Ginowan, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-leucine-rich glioma-inactivated 1 (LGI1) antibody-associated autoimmune encephalitis (anti-LGI1-AE) is a neuronal, surface antibody-mediated type of encephalitis characterized by medial temporal lobe hypertrophy and hyperintensity on T2-weighted images (WI). T1-weighted images (T1WI) can reveal basal ganglia hyperintensity, particularly when patients have faciobrachial dystonic seizures (FBDS). This signal change on T1WI is generally considered to correlate with FBDS. Here, we describe a female patient with FBDS and basal ganglia T1WI hyperintensity in whom imaging abnormalities did not reflect FBDS severity. Although a single observation cannot establish causality, this dissociation raises the possibility that factors other than FBDS activity contribute to altered T1WI signals and that such findings might not always reflect disease activity. Clinicians should be aware that such T1WI changes do not need to parallel FBDS to avoid overinterpreting them as clinical course markers. Further studies are required to clarify these underlying mechanisms.

Indexed as

Autoimmune encephalitisBasal gangliaFaciobrachial dystonic seizureHyperintensityHyponatremiaLeucine-rich glioma-inactivated 1

Identifiers

PMID42500496
PMCPMC13396601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.