Evidence map›Paper›PMID 42500472›Full record

ReviewFrontiers in plant science2026

Next-generation insect pest management: genetic innovations and emerging biocontrol strategies.

Estibaliz Sansinenea, Leandris Argentel-Martínez, Ofelda Peñuelas-Rubio, HeeJoo Hwang, Umut Toprak, Debasis Mitra, A El-Shabasy, Sudhir Kumar Upadhyay, Jae-Ho Shin, Ugur Azizoglu

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Estibaliz SansineneaFacultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, Puebla, Mexico.
Leandris Argentel-MartínezTecnológico Nacional de México/Instituto Tecnológico del Valle del Yaqui, Bácum, Sonora, Mexico.
Ofelda Peñuelas-RubioTecnológico Nacional de México/Instituto Tecnológico del Valle del Yaqui, Bácum, Sonora, Mexico.
HeeJoo HwangDepartment of Integrative Biology, Kyungpook National University, Daegu, Republic of Korea.
Umut ToprakMolecular Entomology (MOLEN) Lab, Faculty of Agriculture, Department of Plant Protection, Ankara University, Ankara, Türkiye.
Debasis MitraDepartment of Microbiology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, India.
A El-ShabasyDepartment of Biology, College of Science, Jazan University, Jazan, Saudi Arabia.
Sudhir Kumar UpadhyayResearch and Development Cell, Lovely Professional University, Phagwara, Punjab, India.
Jae-Ho ShinDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, Republic of Korea.
Ugur AzizogluSafiye Cikrikcioglu Vocational College, Department of Crop and Animal Production, Kayseri University, Kayseri, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pest insects represent a major challenge to agriculture and global food security. Existing insect control methods such as chemical insecticides are under increasing scrutiny because of their environmental impacts, and once-effective methods are facing reduced acceptance due to insect pests evolving resistance and increasing regulation. This review summarizes recent advances in transgenic approaches to insect pest control over the last five years. Transgenic crops and molecular approaches play an important role in integrated pest management strategies. Integration of gene drive and transgene-generated resistance offers new strategies for targeted pest suppression, while novel platforms for delivery of dsRNA and CRISPR have broadened the range of molecular approaches. We analyze the ethical and ecological considerations, including biosafety concerns related to species interactions and gene flow. In addition, we examine the potential and limitations of RNAi and CRISPR, including regulatory challenges and public perception of genetic engineering. Synthetic biology, precision agriculture and good risk governance are central to genetic pest control strategies. Advances at the interface of biotechnology and natural systems offer a pathway toward more sustainable and resilient agricultural practices.

Indexed as

crop protectiongenetic pest controlsmart biocontroltransgenic insectstransgenic plants

Identifiers

PMID42500472
PMCPMC13396169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.