Evidence map›Paper›PMID 42500455›Full record

ArticleAnnals of intensive care2026

Extracorporeal CO

Yuri de Albuquerque Pessoa Dos Santos, Paulo Ricardo Gessolo Lins, Bruno Martins Tomazini, Eduardo Lyra de Queiroz, Laerte Pastore Júnior, Fernando José da Silva Ramos, Maristela Carvalho de Costa, Eduardo Leite Vieira Costa, Marcelo Brito Passos Amato, Alain Combes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of intensive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuri de Albuquerque Pessoa Dos SantosIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Paulo Ricardo Gessolo LinsFederal University of São Paulo (UNIFESP), Rua Napoleão de Barros, 715, Vila Clementino, São Paulo, SP, 04024-002, Brazil.
Bruno Martins TomaziniIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Eduardo Lyra de QueirozIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Laerte Pastore JúniorIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Fernando José da Silva RamosIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Maristela Carvalho de CostaNephrology Service, Heart Institute (InCor), University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 44, São Paulo, SP, 05403-000, Brazil.
Eduardo Leite Vieira CostaIntensive Care Unit, Hospital Sírio-Libanês, Rua Dona Adma Jafet, 91, Bela Vista, São Paulo, SP, 01308-050, Brazil.
Marcelo Brito Passos AmatoRespiratory Intensive Care Unit, School of Medicine, University of São Paulo, Av. Dr. Arnaldo, 455, Cerqueira César, São Paulo, SP, 01246-903, Brazil.
Alain CombesSorbonne Université, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris, Sorbonne Université Hôpital Pitié-Salpêtrière, 47, Boulevard de l'Hôpital, Paris F-75013, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) represent a complex clinical scenario. Permissive hypercapnia during lung-protective ventilation may cause severe acidemia and limit further reductions in ventilatory intensity. Extracorporeal carbon dioxide removal integrated into the CRRT circuit may enhance carbon dioxide clearance while providing renal support, but its physiological effects and safety in this population remain uncertain. Methods: We conducted a systematic review and meta-analysis of adult studies evaluating ECCO Results: Seven observational studies comprising 105 patients were included. ECCO Conclusion: ECCO Trial registration: PROSPERO CRD420251234033.

Indexed as

Acute kidney injuryAcute respiratory distress syndromeContinuous renal replacement therapyHypercapniaPositive-pressure respiration

Identifiers

PMID42500455
PMCPMC13396961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.