Evidence map›Paper›PMID 42500430›Full record

ArticleJournal of the Society for Cardiovascular Angiography & Interventions2026

Cost-Effectiveness of Supersaturated Oxygen Delivery for Infarct Size Reduction in Patients With Anterior ST-Segment Elevation Myocardial Infarction.

Katherine Vilain, Harun Kundi, Bjorn Redfors, Emily M Bucholz, Neel M Butala, David J Cohen

Abstract read
In one paragraph

Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pump Up the OJournal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine VilainUniversity of Missouri-Kansas City's Healthcare Institute for Innovations in Quality, Kansas City, Missouri.
Harun KundiCardiovascular Research Foundation, New York, New York.
Bjorn RedforsCardiovascular Research Foundation, New York, New York.
Emily M BucholzSection of Cardiology, Department of Pediatrics, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Neel M ButalaRocky Mountain Regional VA Medical Center, Aurora, Colorado.
David J CohenCardiovascular Research Foundation, New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocardial infarct size (IS) is a key determinant of long-term outcomes after acute myocardial infarction (MI). Although infusion of supersaturated oxygen (SSO Methods: We developed a Markov model to project long-term mortality, quality of life, and costs among patients with acute anterior STEMI undergoing PPCI. Among surviving patients, we modeled the incidence of post-MI heart failure, cardiovascular death, and noncardiovascular death as a function of IS, using population-based data for calibration. Health state-specific costs were derived from Medicare data. The cost of SSO Results: In our base case analysis (mean age 61 years; 22% female; mean IS 25% of LV mass), treatment with SSO Conclusions: Based on our disease simulation model, SSO

Indexed as

cost-effectivenessdecision analysisheart failuremyocardial infarct sizeST-segment elevation myocardial infarctionsupersaturated oxygen

Identifiers

PMID42500430
PMCPMC13400098

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.