ArticleFrontiers in neurology
Clinical outcomes and bleeding events associated with tirofiban combined with intravenous alteplase in acute ischaemic stroke: a retrospective single-center study.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate the clinical efficacy and bleeding risk of tirofiban combined with intravenous alteplase in patients with acute ischaemic stroke (AIS). Methods: This retrospective study identified 90 AIS patients who were divided according to the treatment received into a combined group (CG, Results: Baseline characteristics were comparable between the two groups ( Conclusion: In this retrospective single-center cohort, tirofiban combined with alteplase was associated with lower NIHSS scores, better post-treatment vascular status, and higher rates of favorable 90-day outcomes, suggesting that combination therapy may potentially improve neurological recovery, attenuate inflammation, and optimize post-treatment vascular status in patients with AIS; however, these findings require confirmation in larger randomized trials.
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