Evidence map›Paper›PMID 42500385›Full record

ReviewMagnetic resonance letters2026

Chemical exchange saturation transfer NMR: An analytical tool and its applications.

Lixia Wang, Jie Cui, Junfeng Xiang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Magnetic resonance letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lixia WangBeijing National Laboratory for Molecular Sciences (BNLMS), Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Jie CuiBeijing National Laboratory for Molecular Sciences (BNLMS), Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Junfeng XiangBeijing National Laboratory for Molecular Sciences (BNLMS), Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NMR spectroscopy has proven to be a powerful tool for elucidating structural information and studying dynamic processes. Among NMR techniques, chemical exchange saturation transfer (CEST) is particularly suitable for investigating systems with slow exchange rates and holds significant promise for tracking metastable intermediates to explore dynamic mechanisms. This review focuses on applications of CEST in chemistry, including: (1) detection of transient species in living systems, (2) kinetic characterization of chemical reactions and conformational changes, and (3) selective recognition facilitated by paramagnetic reagents. The CEST methodology thus offers novel approaches for organic chemists and chemical biologists, while providing insights into dynamic kinetics across diverse research fields.

Indexed as

Chemical exchange saturation transfer (CEST)Chemical reactionConformation transformationDetectionDynamic kinetics

Identifiers

PMID42500385
PMCPMC13398279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.