ArticleJournal of International Society of Preventive & Community Dentistry
HyaluHerb Pediatric Oral Gel for Recurrent Aphthous Ulcers and Plaque-Induced Gingivitis in Children: A Two-Cohort Randomized Controlled Trial.
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Objective: Recurrent aphthous ulcers (RAU) and plaque-induced gingivitis are among the prevalent pediatric oral conditions. Standard treatments such as chlorhexidine (CHX) and topical corticosteroids have limitations, including unpleasant taste, staining, and poor adherence. This study evaluated HyaluHerb, a novel alcohol-free gel containing 0.2% hyaluronic acid (HA), Methods: This was a single-center, double-blind, randomized controlled trial. Cohort A (RAU, Results: In Cohort A, HyaluHerb significantly accelerated ulcer healing versus placebo (median 5.3 vs. 7.2 days; hazard ratio = 1.73, 95% confidence interval [CI]: 1.16-2.59; Conclusion: HyaluHerb is an effective, well-tolerated, child-friendly treatment for acute pediatric RAU and plaque-induced gingivitis.
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