ArticleJournal of International Society of Preventive & Community Dentistry
Physiochemical Analysis of Fluoride Availability and pH in Moroccan Mouthwashes: Clinical Implications for Enamel Safety.
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Objective: Fluoride mouthwashes are essential tools for caries prevention; however, their efficacy and safety depend on accurate fluoride concentrations and non-erosive pH levels. Deviations from labeled specifications can compromise therapeutic outcomes or pose risks to dental enamel. The aim was to quantify the available fluoride concentration and evaluate the pH of commercially available mouthwashes in Morocco, benchmarking them against international ISO standards and clinical safety thresholds. Methods: Twenty commercially available mouthwashes were collected from Moroccan pharmacies and supermarkets. Fluoride concentration was determined using the Belcher-West colorimetric method with Alizarin complexone, based on spectrophotometric measurements at 618 nm following appropriate calibration and method validation. The pH of each product was measured using a calibrated digital pH meter. The accuracy of fluoride labeling was examined based on international quality standards. Statistical analysis included a 15% deviation benchmark (ISO 16408) and Pearson's correlation to assess the relationship between fluoride stability and acidity. Packaging materials (polyethylene terephthalate/high-density polyethylene) were assessed for their impact on physicochemical stability. Results: Among fluoridated mouthwashes, 80% ( Conclusion: A substantial proportion of Moroccan mouthwashes fail to meet international standards for fluoride labeling accuracy. Furthermore, the presence of acidic formulations in the market necessitates stricter regulatory oversight to ensure enamel safety. Clinicians should be cautious when recommending specific low pH formulations to patients with high erosive risk.
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