Evidence map›Paper›PMID 42500271›Full record

ArticlePsychiatric research and clinical practice2026

Resisting Contagious Hopelessness: Therapeutic Alliance and the Limits of Physician-Assisted Death in Severe and Enduring Anorexia Nervosa.

Elizabeth M Olson, Fabian M Saleh, Angela S Guarda

Abstract read
In one paragraph

Article in Psychiatric research and clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth M OlsonDepartment of Psychiatry and Behavioral Sciences Johns Hopkins School of Medicine Baltimore Maryland USA.
Fabian M SalehDepartment of Psychiatry and Behavioral Sciences Johns Hopkins School of Medicine Baltimore Maryland USA.
Angela S GuardaDepartment of Psychiatry and Behavioral Sciences Johns Hopkins School of Medicine Baltimore Maryland USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contemporary psychiatric ethics emphasize autonomy and shared decision-making, yet these frameworks may be strained in severe mental illnesses characterized by cognitive rigidity, fluctuating decisional capacity, and undue clinician influence. Severe and enduring anorexia nervosa serves as a case example to explore how therapeutic alliance, clinician expectations, and suggestibility may shape expressions of choice in high-stakes decision-making, including discussions of physician-assisted death. Drawing on psychotherapy theory, placebo science, and clinical outcome data, this paper argues that clinician framing and prognostic stance function as treatment variables that may transmit either hope or hopelessness. Ongoing therapeutic engagement focused on improving quality of life and the instillation and preservation of hope should precede any consideration of end-of-life interventions.

Identifiers

PMID42500271
PMCPMC13398815

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.