Evidence map›Paper›PMID 42500249›Full record

ArticleFrontiers in nutrition2026

Short-term ketogenic diet induces systemic lipidomic remodeling associated with metabolic adaptation in humans.

Minkuk Park, Jae Sik Yu, Justin Y Jeon, Hyun-A Oh, Yong-Ho Lee, Sang-Guk Lee, Gakyung Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minkuk ParkDepartment of Integrative Biological Sciences and Industry, Sejong University, Seoul, Republic of Korea.
Jae Sik YuDepartment of Integrative Biological Sciences and Industry, Sejong University, Seoul, Republic of Korea.
Justin Y JeonCenter for Exercise Medicine and Salutogenesis, ICONS & Department of Sport Industries, Yonsei University, Seoul, Republic of Korea.
Hyun-A OhCheongju-Osong National Advanced CTC (CONACTC), Chungbuk National University Hospital, Cheongju, Republic of Korea.
Yong-Ho LeeDivision of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Sang-Guk LeeDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Gakyung LeeDepartment of Integrative Biological Sciences and Industry, Sejong University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ketogenic diet (KD) induces a shift in systemic energy metabolism toward fatty acid oxidation and ketone body production, but its impact on lipid species-level remodeling and insulin sensitivity in humans remains incompletely characterized. We aimed to characterize short-term KD-induced changes in circulating metabolites and lipid profiles and their relationships with insulin sensitivity in healthy adults. Fifteen participants (24-38 years) underwent a 3-day isocaloric KD (75% fat, 20% protein, 5% carbohydrate) under controlled conditions. Serum samples collected before and after the intervention were profiled using metabolomics and lipidomics. KD was associated with increased circulating acylcarnitines, acetyl-L-carnitine, and

Indexed as

ether-linked phospholipidinsulin sensitivityketogenic dietlipidomicsmetabolomics

Identifiers

PMID42500249
PMCPMC13395721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.