ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2026
Effectiveness of single-dose methotrexate in the treatment of ectopic pregnancy: a retrospective study.
Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Evaluate the effectiveness of Methotrexate in clinical treatment of ectopic pregnancy and analyze the influence of clinical and laboratory variables on the treatment outcome. Methods: It was a retrospective study of 95 patients undergoing clinical treatment with Methotrexate at a private tertiary hospital in the metropolitan region of Belo Horizonte. Variables such as age, presence of pelvic pain, previous ectopic pregnancy, initial beta-hCG level and largest adnexal mass measurement were analyzed. The theoretical framework followed a data search in PubMed, selecting 17 articles in total. Results: The clinical success rate with a dose of Methotrexate was 71,6%. Among the variables evaluated, only the initial beta-hCG value showed statistical significance with the outcome, therefore, higher the beta-hCG, lower the chance of treatment effectiveness, with a p-value of 0.002. The other variables analyzed did not show any significant association. Conclusion: Methotrexate has been shown to be effective in most cases of ectopic pregnancy, with the initial beta-hCG value standing out as a predictor of treatment failure. The findings reinforce the importance of adequate patient selection and laboratory monitoring in clinical follow-up.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.