ArticleWorld journal of otorhinolaryngology - head and neck surgery2026
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000-2018).
Article in World journal of otorhinolaryngology - head and neck surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000-2018).World journal of otorhinolaryngology - head and neck surgery · 2026Article
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17 authors.
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Abstract
Background: Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high-power field, requiring accuracy optimization. Methods: In this retrospective study, 970 CRS patients in Guangzhou from 2000 to 2018 undergoing endoscopic sinus surgery were divided into five biennial cohorts. Demographic, clinical, and pathological data were analyzed to compare subgroup differences and assess correlations between pathological features and urbanization indicators, including land use, socioeconomic status, and motor vehicle ownership. Pathological outcomes were assessed via artificial intelligence‑based whole-slide imaging. Results: Allergic comorbidity of CRS patients increased from 5.38% to 15.36% ( Conclusions: Among CRS patients in Guangzhou, pathological overall inflammation and eosinophilic infiltration progressively increased, while the proportion of lymphocytes declined. Additionally, urbanization indicators, notably population density, were strongly associated with shifts in the inflammatory profile and the rising prevalence of allergic comorbidities.
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