Evidence map›Paper›PMID 42500045›Full record

ArticleFood chemistry: X2026

Integrated microbiome and metabolome analyses reveal spatial heterogeneity of medium-temperature Daqu and its potential impact on simulated strong-flavor baijiu fermentation.

Zhang Wen, Yu-Hua Wei, Hai-Yan Zhu, Liang Song, Da-Yong Han, Liang-Chen Guo, Chao-Jiu He, Zheng-Xiang Guo, Pei-Jie Han

Abstract read
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhang WenState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Yu-Hua WeiState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Hai-Yan ZhuState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Liang SongState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Da-Yong HanState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Liang-Chen GuoState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.
Chao-Jiu HeJin Brand Nanxi Liquor Industry (Yibin) Co., Ltd., Yibin 629133, PR China.
Zheng-Xiang GuoJin Brand Nanxi Liquor Industry (Yibin) Co., Ltd., Yibin 629133, PR China.
Pei-Jie HanState Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medium-temperature Daqu (MTD) exhibits pronounced spatial heterogeneity between its surface (QS) and inner (QI) portions, yet their functional differences remain poorly understood. This study compared physicochemical properties, metabolites, and species-level microbial communities of QS and QI and evaluated their impacts on simulated strong-flavor Baijiu (SFB) fermentation. QS exhibited higher saccharification and liquefaction activities and higher counts of lactic acid bacteria and yeasts, whereas QI was enriched in thermophilic molds and volatile compounds. Thirty-two microbial biomarkers differentiated QS and QI, and QS showed a more complex microbial co-occurrence pattern. Simulated fermentation revealed early bacterial divergence followed by convergence to

Indexed as

Functional heterogeneityMedium-temperature DaquMetabolic phenotypeSolid-state simulated fermentationSpatial heterogeneityStrong-flavor baijiu

Identifiers

PMID42500045
PMCPMC13396755

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.