ArticleFrontiers in public health2026
E-health literacy is associated with better medication adherence in older adults with chronic comorbidities: the mediating role of information overload and the moderating effect of family care on the anxiety-adherence link.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Using the Stimulus-Organism-Response and stress buffering models, this study explores how e-health literacy is associated with medication adherence in older adults with chronic comorbidities, focusing on the chained mediation of information overload/anxiety and the moderation of family care on anxiety-adherence. Method: A cross-sectional survey was conducted (October 2025-March 2026) on 428 eligible adults (conveniently sampled from 3 Grade A tertiary hospitals in Northwest China). Assessments used 5 scales (Electronic Health Literacy, Information Overload Severity, Self-Rating Anxiety, Family Care Index, Morisky Medication Adherence). We performed analyses (correlation, stratified regression, structural equation modeling) using SPSS 29.0 and AMOS 26.0. Results: Medication adherence was poor (80.8% non-adherent), with good model fit. E-health literacy was directly associated with adherence ( Conclusion: E-health literacy is associated with better adherence in older adults with chronic comorbidities (directly or through reduced information overload), while family care is associated with a weaker negative impact of anxiety on medication behavior. This "moderated mediation" model suggests future interventions may benefit from improving elderly e-health literacy and integrate family care for targeted multi-level strategies.
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