Evidence map›Paper›PMID 42499974›Full record

ArticleWorld journal of emergency medicine2026

Emergency transfusion of uncross-matched O-type red blood cells in patients with severe pelvic fracture: a multi-center propensity score-weighted analysis.

Hui Li, Yong Fu, Anyong Yu, Guangbin Huang, Yong Luo, Yunfeng Yi, Gongliang Du, Xingwen Zhang, Eryue Qiu, Cai Lin and 3 more

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Article in World journal of emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Hui Li1Department of Emergency Medicine, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Yong Fu2Trauma Center, Pediatric Orthopedic Department, Hand and Foot Surgery, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.
Anyong Yu3Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.
Guangbin Huang4Department of Traumatology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.
Yong Luo5Emergency Department, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.
Yunfeng Yi6Department of Cardiothoracic Surgery, the 909th Hospital, School of Medicine, Xiamen University, Zhangzhou 363000, China.
Gongliang Du7Department of Emergency Surgery, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
Xingwen Zhang8Department of Emergency Medicine, Hunan Provincial People's Hospital, First Affiliated Hospital of Hunan Normal University, Changsha 410005, China.
Eryue Qiu9Trauma Center, Xiangya Hospital Zhuzhou Central South University, Central South University, Zhuzhou 412007, China.
Cai Lin10Department of Emergency Surgery, Huizhou First Hospital, the First Huizhou Affiliated Hospital of Guangdong Medical University, Huizhou 516000, China.
Fei Xia11Department of Emergency, the Affiliated Hospital, Guiyang Medical University, Guizhou 550004, China.
Dingyuan Du4Department of Traumatology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, China.
Mao Zhang1Department of Emergency Medicine, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe transfusion of uncross-matched O-type red blood cells (URBCs) is the global standard of care for emergency resuscitation in trauma. However, its application in China remains limited due to concerns over safety and resource availability. This study aimed to evaluate the clinical efficacy and safety of URBCs in patients with severe pelvic fractures.

methodsIn this multicenter, retrospective cohort study (2019-2023), patients with severe pelvic fractures (Abbreviated Injury Scale [AIS]≥3) transfused within 24 h of admission were stratified into the URBC and non-URBC groups. Propensity score overlap weighting (PSOW) was used to address confounding factors. The primary outcome was 30-day in-hospital mortality. Secondary outcomes included length of stay (LOS), 24-hour blood product consumption, and in-hospital complications.

resultsA total of 526 patients were included (URBC group,

conclusionEarly administration of URBCs for severe pelvic fractures is safe. While not associated with increased mortality or hemolytic transfusion reactions, early use of URBCs was linked to a significant reduction in coagulation-related blood product consumption. This study provides evidence supporting the implementation of URBC within resource-constrained trauma setting to improve resuscitation efficiency.

Indexed as

Multicenter studyO-type red blood cellsPelvic fracturePropensity scoreTrauma resuscitationUncross-matched

Identifiers

PMID42499974
PMCPMC13395589

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