ArticleFrontiers in cardiovascular medicine2026
Assessment of cardioprotective activity of a nitrate enriched food-based polyherbal formulation using experimental myocardial infarction in rats.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Recently, Myocardial infarction (MI) became the foremost causes of mortality globally. Growing modern pharmacological evidences indicate that food based herbal formulations can offer promising therapeutic benefits in the management of cardiovascular diseases. Materials and methods: In the current study, we investigated the therapeutic potential of a newly developed nitrate-enriched extract from Results: LAD-induced MI significantly increased LDH, CK-MB, oxidative stress, and cardiac inflammation. However, treatment with Oxystorm and its turmeric blend alleviated levels of lactate enzyme, CK-MB, troponin-I, interleukins, and malondialdehyde, which reduced infarct size, though enhanced antioxidant defense (GSH and SOD). Conclusion: The enriched dietary nitrate content in Oxystorm, when combined with polyphenol-rich turmeric extract (BCM-95), showed cardioprotective potential, which may be associated with nitrate/NO-related mechanisms, attenuation of oxidative stress, and suppression of inflammatory pathways. However, nitric oxide bioavailability and related signaling pathways were not directly assessed in the present study. Taken together, the pioneer observations, suggest that Oxystorm and its turmeric combination, may serve as adjuvants for the management of ischemia and related cardiac diseases.
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