Evidence map›Paper›PMID 42499788›Full record

ArticleHealth science reports2026

Improvement in the Microbiological Diagnosis of Hepatitis D on the Mediterranean Coast of Southeastern Spain: A Repeated Cross-Sectional Survey.

Maria Paz Ventero, Iryna Tyshkovska, Jose Carlos Castillo-Sanchez, Sergio Reus, Alba de la Rica, Nieves Orta, Conxa Serrat, Maria Gil, Victoria Ortiz de la Tabla, David Navarro and 18 more

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Maria Paz VenteroMicrobiology Service Alicante General University Hospital - Alicante Institute of Health and Biomedical Research (ISABIAL) Alicante Spain.ORCID https://orcid.org/0000-0003-1979-0949
Iryna TyshkovskaMicrobiology Service Alicante General University Hospital - Alicante Institute of Health and Biomedical Research (ISABIAL) Alicante Spain.
Jose Carlos Castillo-SanchezMicrobiology Service Alicante General University Hospital - Alicante Institute of Health and Biomedical Research (ISABIAL) Alicante Spain.
Sergio ReusUnit of Infectious Diseases Alicante General University Hospital - Alicante Institute of Health and Biomedical Research (ISABIAL) Alicante Spain.
Alba de la RicaMicrobiology Service Torrevieja University Hospital Torrevieja Spain.
Nieves OrtaMicrobiology Service Francesc of Borja Hospital Gandía Spain.
Conxa SerratMicrobiology Service La Pedrera Hospital Denia Spain.
Maria GilMicrobiology Service La Plana University Hospital Vila-Real Spain.
Victoria Ortiz de la TablaMicrobiology Service Sant Joan D'Alacant Hospital San Juan Spain.
David NavarroMicrobiology Service Valencia Clinical University Hospital Valencia Spain.ORCID https://orcid.org/0000-0003-3010-4110
Sofia BeldaMicrobiology Service Vega Baja Hospital Orihuela Spain.
Olalla MartinezMicrobiology Service La Ribera Hospital Alcira Spain.
Javier CoyMicrobiology Service Marina Salud Denia Hospital Denia Spain.
Victoria SimónMicrobiology Service Sagunto Hospital Sagunto Spain.
Josefina MagranerMicrobiology Service Castellon Provincial Hospital Castellon Spain.
Concepcion GimenoMicrobiology Service Valencia General University Hospital Valencia Spain.
Maruan ShalabiMicrobiology Service Marina Baixa Hospital Villajoyosa Spain.
Jose María Garcia-AguayoMicrobiology Service Requena Hospital Requena Spain.
M Dolores Tirado-BalaguerMicrobiology Service Castellon General University Hospital Castellón Spain.
Victoria DominguezMicrobiology Service Arnau of Vilanova Hospital Valencia Spain.
M Montserrat RuizMicrobiology Service Elche General University Hospital Elche Spain.
Isabel GascónMicrobiology Service Elda General University Hospital Elda Spain.
Mercedes RoigMicrobiology Service Vinaroz Regional Hospital Vinaroz Spain.
Salvador GinerMicrobiology Service La Fe University and Polytechnic Hospital Valencia Spain.
Rosa GonzálezMicrobiology Service Dr. Peset University Hospital Valencia Spain.
Encarna FuentesMicrobiology Service Virgen de los Lirios Hospital Alcoi Spain.
Coral LlopisMicrobiology Service Vinalopo Hospital Elche Spain.
Juan Carlos RodriguezMicrobiology Service Alicante General University Hospital - Alicante Institute of Health and Biomedical Research (ISABIAL) Alicante Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hepatitis D virus (HDV) remains underdiagnosed, and universal screening of HBsAg-positive patients is recommended. We assessed changes in HDV diagnostic capacity across public hospitals in the Valencian Community, Spain. Methods: Repeated cross-sectional surveys were conducted in 2024 and 2025. Analyses included the 19 hospitals participating in both years and evaluated anti-HDV testing, HDV RNA detection, reflex testing, and clinician notification. Results: Anti-HDV testing increased from 84.2% to 94.7%, HDV RNA testing from 68.4% to 84.2%, reflex testing from 43.8% to 77.8% ( Conclusions: HDV diagnostic capacity improved substantially, particularly in smaller hospitals. Further organizational measures are needed to achieve universal double-reflex testing and timely communication of positive results.

Identifiers

PMID42499788
PMCPMC13396877

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.