Evidence map›Paper›PMID 42499708›Full record

ReviewFrontiers in cell and developmental biology2026

RNA modifications in radiotherapy resistance and radiosensitization: epitranscriptomic regulation of tumor response to radiation.

Hongran Qin, Shuqiang Yang, Jiawei He, Meijia Zhao, Luqian Zhao, Jingjing Wang, Xiulin Jiang, Xin Xu, Xiaowen Chen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongran Qin *Department of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Shuqiang Yang *Department of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Jiawei HeDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Meijia ZhaoDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Luqian ZhaoDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Jingjing WangDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Xiulin JiangCollege of Life Science, University of Chinese Academy of Sciences, Beijing, China.
Xin XuDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Xiaowen ChenDepartment of Nuclear Radiation, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy (RT) remains a major treatment for solid tumors, but durable tumor control is frequently limited by adaptive DNA repair, altered cell-death thresholds, cancer stemness, metabolic plasticity, and immune escape. RNA modifications have recently emerged as rapid post-transcriptional regulators that enable tumor, stromal, and immune cells to remodel these programs after irradiation. This Mini Review emphasizes three major themes. First, N

Indexed as

DNA damage repairepitranscriptomicsferroptosisradioresistanceradiosensitizationradiotherapyRNA modificationstumor microenvironment

Identifiers

PMID42499708
PMCPMC13396160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.