Evidence map›Paper›PMID 42499673›Full record

ArticleActa naturae

Long Non-Coding RNAs: Allies and Enemies of HIV Infection.

T F Kikhai, A V Mashkovskaia, T S Oretskaya, Y Y Agapkina, M B Gottikh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

T F KikhaiLomonosov Moscow State University, Faculty of Chemistry, Moscow, 119991 Russia.
A V MashkovskaiaLomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics, Moscow, 119991 Russia.
T S OretskayaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119991 Russia.
Y Y AgapkinaLomonosov Moscow State University, Faculty of Chemistry, Moscow, 119991 Russia.
M B GottikhLomonosov Moscow State University, Faculty of Chemistry, Moscow, 119991 Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significant impact on the pathogenesis of viral infections by acting as both positive and negative regulators of viral gene expression. This review summarizes the available data on lncRNAs associated with human immunodeficiency virus type 1 (HIV-1). LncRNAs can regulate both the active replication cycle and the latent phase of the HIV-1 infection, during which the integrated proviral DNA remains transcriptionally silent. Moreover, lncRNAs may serve as diagnostic markers and are potential therapeutic targets. A deeper understanding of the intricate interactions between lncRNAs and HIV-1 is essential for developing innovative treatments for the HIV infection and the associated acquired immunodeficiency syndrome (AIDS).

Indexed as

human immunodeficiency viruslatencylong non-coding RNAviral replication

Identifiers

PMID42499673
PMCPMC13399665

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.