Evidence map›Paper›PMID 42499588›Full record

ArticleJournal of arrhythmia2026

Successful Defibrillation After Conversion From Fixed-Tilt to Tuned-Duration Waveform.

Yousaku Okubo, Hisayasu Matsuzaki, Shogo Miyamoto, Hiroshi Oe, Yukiko Nakano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of arrhythmia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yousaku OkuboDepartment of Cardiovascular Medicine Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan.ORCID https://orcid.org/0000-0003-4034-5356
Hisayasu MatsuzakiDivision of Clinical Engineering, Clinical Support Department Hiroshima University Hospital Hiroshima Japan.
Shogo MiyamotoDepartment of Cardiovascular Medicine Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan.
Hiroshi OeDepartment of Cardiovascular Medicine Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan.
Yukiko NakanoDepartment of Cardiovascular Medicine Hiroshima University Graduate School of Biomedical and Health Sciences Hiroshima Japan.ORCID https://orcid.org/0000-0001-5373-5164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fixed-tilt biphasic shocks may become ineffective in high-impedance states because phase-2 over-prolongation disrupts optimal charge neutralization. Waveform tuning based on membrane time constants, as implemented by DeFT Response, shortens phase durations to physiologic ranges and lowers the defibrillation threshold. This mechanism-based strategy may enhance the reliability of ICD therapy in patients with rising impedance or high DFTs.

Indexed as

DeFT responsehigh defibrillation thresholdimplantable cardioverter‐defibrillatorssudden cardiac deathtuned defibrillation waveformsventricular fibrillationventricular tachycardia

Identifiers

PMID42499588
PMCPMC13396872

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.