Evidence map›Paper›PMID 42499581›Full record

ArticleMolecular genetics and metabolism reports2026

Proteomic alterations in patient bone-derived stromal cells and their secretomes in osteogenesis imperfecta.

Kishore Garapati, Dong-Gi Mun, Rex Devasahayam Arokia Balaya, Mayank Saraswat, Santosh Renuse, Gregory Trahan, Richard K Kandasamy, David R Deyle, Akhilesh Pandey

Abstract read
In one paragraph

Article in Molecular genetics and metabolism reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kishore GarapatiManipal Academy of Higher Education (MAHE), Manipal, Karnataka, India.
Dong-Gi MunDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Rex Devasahayam Arokia BalayaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Mayank SaraswatDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Santosh RenuseDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Gregory TrahanDepartment of Clinical Genomics, Mayo Clinic, Rochester, MN, USA.
Richard K KandasamyDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
David R DeyleDepartment of Clinical Genomics, Mayo Clinic, Rochester, MN, USA.
Akhilesh PandeyDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Type I collagen is the most abundant form of collagen and forms the organic component of bone. Pathogenic variants in genes encoding its constituent polypeptide chains,

Indexed as

Bone developmentExtracellular matrixGenetic disorder

Identifiers

PMID42499581
PMCPMC13396962

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.