Evidence map›Paper›PMID 42499469›Full record

ArticleAnnals of Ibadan postgraduate medicine2026

PREVALENCE, CHARACTERISTICS AND TREATMENT OUTCOMES OF HPV POSITIVE OROPHARYNGEAL CARCINOMA IN AFRICA: A SYSTEMATIC REVIEW AND META-ANALYaSIS.

V Somoye, A E Babalola, A O Ogwuche, O Bolarinwa, O Onasanya, K Giwa, V Johnson, O Azeez, T Williams

Abstract read
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In one paragraph

Article in Annals of Ibadan postgraduate medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

V SomoyeFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
A E BabalolaKornberg School of Dentistry, Temple University, Philadelphia, USA.
A O OgwucheCollege of Medicine, University of Ilorin, Ilorin, Nigeria.
O BolarinwaJohns Hopkins University, Maryland, USA.
O OnasanyaFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
K GiwaFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
V JohnsonFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
O AzeezFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
T WilliamsInstitute for Health and Equity, Medical College of Wisconsin, Wisconsin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Human papillomavirus (HPV) is a sexually transmitted virus implicated in several anogenital and oropharyngeal malignancies. Rising oral sexual practices have been suggested as one factor influencing oral HPV transmission and associated malignancies in some populations. This review aimed to estimate the pooled prevalence, summarize characteristics, and synthesize treatment and outcome data for HPV-positive oropharyngeal carcinoma (OPC) in Africa. Methods: An initial PROSPERO registration was done (CRD420251012776), and the systematic review followed the PRISMA guidelines. The study included original English peer-reviewed research works that reported data on the prevalence, characteristics, and treatment outcomes of HPV-positive oropharyngeal cancers. The risk of bias was assessed for all the studies using Cochrane's ROBIN-E tool. Systematic synthesis and meta-analysis were used to synthesise extracted data. Results: 15 studies involving a total of 896 participants met the inclusion criteria and were included in the meta-analysis. The pooled prevalence of HPV-associated oropharyngeal cancer across the 15 African-based studies was 12% (95% CI: 8%-19%), with significant heterogeneity (I Conclusion: There were limited data of treatment and outcomes underscoring the need for improved reporting standards and longitudinal data across African settings.

Indexed as

AfricaHPV PrevalenceHuman papilloma virusOral HPVOropharyngeal carcinoma

Identifiers

PMID42499469
PMCPMC13399177

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.