Evidence map›Paper›PMID 42499443›Full record

ArticleTurkish journal of medical sciences2026

Skin cancer surgery under local anesthesia: clinicopathologic characteristics and age-stratified outcomes in 533 patients.

Menekşe Kastamoni Başkan, Süleyman Çeçen, Selçuk Akin, Şaduman Balaban Adim, Güzin Yeşim Özgenel

Abstract read
In one paragraph

Article in Turkish journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Menekşe Kastamoni BaşkanDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Uludag University, Bursa, Turkiye.ORCID https://orcid.org/0000-0002-4667-1550
Süleyman ÇeçenDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Uludag University, Bursa, Turkiye.ORCID https://orcid.org/0000-0003-2430-727X
Selçuk AkinDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Uludag University, Bursa, Turkiye.ORCID https://orcid.org/0000-0003-1683-0722
Şaduman Balaban AdimDepartment of Pathology, Faculty of Medicine, Uludag University, Bursa, Turkiye.ORCID https://orcid.org/0000-0002-5039-164X
Güzin Yeşim ÖzgenelDepartment of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Uludag University, Bursa, Turkiye.ORCID https://orcid.org/0000-0003-0000-8355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Skin cancer is the most common malignancy worldwide, particularly among elderly individuals. Many lesions are detected at an early stage because of their visibility and can be excised under local anesthesia, thereby avoiding the risks associated with general anesthesia or sedation. This study aimed to evaluate patient- and tumor-related characteristics in skin cancer surgery performed under local anesthesia, with particular emphasis on age-related outcomes. Materials and methods: This retrospective study included 533 patients with 613 histopathologically confirmed skin cancers excised under local anesthesia between 2019 and 2024. Demographic, histopathological, and surgical variables were recorded, including age, sex, tumor location, measured tumor area, histologic subtype, surgical margin status, reconstruction technique, and comorbid conditions. Patients were stratified into three age groups (<60, 60-80, and >80 years) for subgroup analyses. Statistical analyses were performed using the Mann-Whitney U test, Kruskal-Wallis test, chi-square test, and Spearman correlation analysis (SPSS version 26.0; IBM Corp., Armonk, NY, USA), with statistical significance set at p < 0.05. Results: The mean patient age was 68.5 years. Most lesions (86.1%) were located in the head and neck region. Basal cell carcinoma (65.4%) and squamous cell carcinoma (21.0%) were the predominant histopathological diagnoses. Primary closure (43.8%) and full-thickness skin grafting (25.0%) were the most frequently performed reconstruction methods. Larger tumor area was significantly associated with positive surgical margins (p < 0.01), and tumor type was significantly associated with both surgical margin status and reconstruction method (p < 0.0001). Age showed a statistically significant positive correlation with tumor area (p = 2.22 × 10 Conclusion: Skin cancer surgery performed under local anesthesia appears to be safe and effective across age groups, including elderly and comorbid patients. Tumor type and tumor area were significantly associated with surgical margin status and reconstruction method. These findings support age-conscious and anesthesia-sparing approaches in oncologic dermatologic surgery.

Indexed as

Anesthesia, LocalSkin NeoplasmsAgedAged, 80 and overAge FactorsBasal Cell CarcinomaCarcinoma, Squamous CellFemaleHumansMaleMargins of ExcisionMiddle AgedRetrospective StudiesTreatment Outcomeagedlocal anesthesiareconstructive surgical proceduresSkin neoplasmssurgical margins

Identifiers

PMID42499443
PMCPMC13398587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.