Evidence map›Paper›PMID 42499421›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2026

Acceptance of deceased donor livers in the United Kingdom - development of a liver "donor utilisation index".

Jennifer Mehew, Helen Thomas, Peter Friend, Simon Knight

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The perfused liver utilisation study (PLUS): challenges and innovation in the evaluation of an emerging technology.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer MehewStatistics and Clinical Research, NHS Blood and Transplant, Bristol, United Kingdom.
Helen ThomasStatistics and Clinical Research, NHS Blood and Transplant, Bristol, United Kingdom.
Peter FriendDepartment of Surgical Sciences, University of Oxford Nuffield, Oxford, United Kingdom.
Simon KnightDepartment of Surgical Sciences, University of Oxford Nuffield, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Published Donor Risk Indices are often used to estimate the risk associated with transplanting a donor liver. Such indices have been constructed by considering only livers that are transplanted and estimating the risk of graft loss or patient death. Until now, there has been no index available that reflects the chance of an offered organ not being transplanted in the United Kingdom (UK). This paper presents a UK Donor Utilisation Index (UKDUI) which quantifies the impact of donor factors upon liver non-use. By comparing our developed UKDUI with a commonly used UK Donor Risk Index, we are able to see that there are differences between the factors that influence liver non-use and the factors that influence liver post-transplant outcomes. Importantly, this UKDUI can be used in future studies to characterise and identify offered livers that are either more or less likely to be transplanted. For example, the UKDUI can be used for study inclusion criteria or for risk adjustment/stratification.

Indexed as

Liver TransplantationTissue and Organ ProcurementTissue DonorsAdultAgedDonor SelectionFemaleHumansMaleMiddle AgedRisk AssessmentUnited Kingdomdonation after brain deathdonation after circulatory deathliver transplantationorgan donationorgan utilisation

Identifiers

PMID42499421
PMCPMC13395755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.