Evidence map›Paper›PMID 42499380›Full record

ReviewPublic health reviews2026

Personalised prevention and management of kidney stones: a narrative review on the importance of integrating environmental, social and genetic factors.

Aleksandra Leonova, Rosa Sinisi, Stefano Alba, Vincenzo Andracchio, Alberto Piana, Carmela Leonessa, Giuseppina Rose, Vito Summa, Giuseppe Passarino, Paolina Crocco

Abstract readReview
In one paragraph

Review in Public health reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aleksandra LeonovaDepartment of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, Italy.
Rosa SinisiInstitute of Methodologies for the Environmental Analysis, National Research Council, Tito Scalo, Italy.
Stefano AlbaRomolo Hospital, Rocca di Neto (KR), Italy.
Vincenzo AndracchioRomolo Hospital, Rocca di Neto (KR), Italy.
Alberto PianaRomolo Hospital, Rocca di Neto (KR), Italy.
Carmela LeonessaInstitute of Methodologies for the Environmental Analysis, National Research Council, Tito Scalo, Italy.
Giuseppina RoseDepartment of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, Italy.
Vito SummaInstitute of Methodologies for the Environmental Analysis, National Research Council, Tito Scalo, Italy.
Giuseppe PassarinoDepartment of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, Italy.
Paolina CroccoDepartment of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney stone disease (KSD) is a prevalent, multifactorial, and common disorder influenced by environmental and genetic factors, with increasing global incidence and high recurrence rates. Despite advances, understanding the interplay between urinary biochemistry, lifestyle, climate, and genetic predispositions remains essential for effective management. In this review, we evaluate current concepts on KSD pathophysiology, epidemiology, stone composition, and formation mechanisms, alongside recent diagnostic and therapeutic developments. We emphasize integrating genetic, environmental, and clinical data to inform personalized prevention and treatment strategies. These insights support tailored approaches that may improve patient outcomes and reduce recurrence, highlighting the potential of personalized medicine in addressing the complex etiology of KSD.

Indexed as

environmental factorsgenetic predispositionkidney stonespersonalized medicinepreventionpro-lithogenic diet

Identifiers

PMID42499380
PMCPMC13396294

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.