ArticleNeuroprotection (Chichester, England)2026
Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease.
Article in Neuroprotection (Chichester, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease.Neuroprotection (Chichester, England) · 2026Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Parkinson's disease (PD) involves progressive gray matter (GM) atrophy, but stage-specific imaging patterns and their genetic mechanisms remain unclear. This study aimed to characterize GM atrophy across PD stages and link these patterns to transcriptional profiles. Methods: A total of 542 patients with PD were obtained from the Parkinson's Progression Markers Initiative (PPMI) database, including early-stage (<2.5 years, Results: Compared to early-stage PD, the mid-stage showed brain GM atrophy in brain regions such as the right angular gyrus, superior temporal gyrus, and middle frontal gyrus ( Conclusion: Progressive GM atrophy in PD reflects coordinated but stage-differentiated molecular processes, revealing cellular and genetic architectures underlying disease progression.
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