Evidence map›Paper›PMID 42499326›Full record

ArticlePNAS nexus2026

Reduced integrity in the frontal aslant tract's premotor connections is associated with dysfluency severity in stuttering.

Maëva Michon, Fabrice Hirsch, Ivana Didirková, Davide Giampiccolo, Marie-Claude Monfrais-Pfauwadel, Anne-Laure Lemaitre, Jérémy Deverdun, Emmanuelle Lebars, Guillaume Herbet

Abstract read
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maëva MichonLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.ORCID https://orcid.org/0000-0002-5597-3067
Fabrice HirschLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.ORCID https://orcid.org/0000-0002-5646-4651
Ivana DidirkováLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.ORCID https://orcid.org/0000-0001-8107-2361
Davide GiampiccoloDepartment of Epilepsy, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, United Kingdom.ORCID https://orcid.org/0000-0003-3849-4168
Marie-Claude Monfrais-PfauwadelLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.
Anne-Laure LemaitreLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.
Jérémy DeverdunDepartment of Neurosurgery, Gui de Chauliac Hospital, Montpellier University Medical Center, Montpellier 34295, France.
Emmanuelle LebarsDepartment of Neurosurgery, Gui de Chauliac Hospital, Montpellier University Medical Center, Montpellier 34295, France.
Guillaume HerbetLaboratoire Praxiling, UMR 5267-CNRS, Université Paul Valéry, Montpellier 34000, France.ORCID https://orcid.org/0000-0001-6690-254X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stuttering is a neurodevelopmental disorder marked by impaired speech production and substantial interindividual variability in symptom severity. Although neuroimaging studies have identified abnormalities in the basal ganglia-thalamocortical circuitry, the specific white matter pathways that underpin dysfluent speech production remain poorly understood. Here, we focus on the frontal aslant tract (FAT), a dorsoventral intralobar tract connecting the superior and inferior frontal cortices and proposed to support both cognitive and motor functions. Using diffusion MRI, we first compared the quantitative anisotropy of the FAT and relevant control tracts in individuals who stutter (

Indexed as

frontal aslant tractpremotor cortexspeech fluencystutteringtractography

Identifiers

PMID42499326
PMCPMC13398998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.