Evidence map›Paper›PMID 42499137›Full record

ArticleJournal of viral hepatitis2026

The Silent Burden of Hepatitis B-Related Stigma.

Verity Smith, Menita Asriah, Katherine Fernelius, Joyeta Das, Laura Grant, Vera Gielen, Shannon Keith

Abstract read
In one paragraph

Article in Journal of viral hepatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Silent Burden of Hepatitis B-Related Stigma.Journal of viral hepatitis · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Verity SmithAdelphi Values Ltd., Patient Centered Outcomes, Cheshire, UK.ORCID https://orcid.org/0009-0006-7148-6425
Menita AsriahAdelphi Values Ltd., Patient Centered Outcomes, Cheshire, UK.
Katherine FerneliusAdelphi Values Ltd., Patient Centered Outcomes, Cheshire, UK.
Joyeta DasGSK, London, UK.
Laura GrantAdelphi Values Ltd., Patient Centered Outcomes, Cheshire, UK.
Vera GielenGSK, London, UK.
Shannon KeithGSK, Wilmington, Delaware, USA.ORCID https://orcid.org/0009-0004-8240-1648

Funding

GlaxoSmithKline Services Unlimited 212750
6 · The paper itself

Abstract

Individuals experiencing stigma related to chronic hepatitis B virus (HBV) infection often experience negative self-beliefs, isolation, discrimination, and reduced willingness to engage with healthcare professionals. We aimed to understand the patient perspective of HBV-related stigma and to summarize the patient experience of stigma in a patient-centric conceptual model. Eligible adult participants with a confirmed diagnosis of chronic HBV infection were recruited from the US, China, and Poland. Qualitative, semi-structured, concept elicitation interviews of approximately 60 min were conducted to explore participants' experiences of stigma. Qualitative analysis of interview data was conducted using Thematic Analysis methods with concepts categorized into domains and pre-determined stigma types. A total of 28 participants were recruited from the US (n = 11), China (n = 11), and Poland (n = 6). Internalized stigma was reported by all participants (n = 28; 100%), social stigma was reported by 79% (n = 22) of participants, and institutional stigma was reported by 57% (n = 16) of participants. Seven domains across condition-specific and health-related quality of life (HRQoL) concepts were identified to create a patient-centric conceptual model of the experience of stigma associated with HBV infection. Each domain was reported by at least half of the participants, with social functioning (n = 28; 100%), emotional wellbeing (n = 27; 96%), and HBV transmission (n = 27; 96%) most frequently reported. Experiences of stigma were highly inter-related. Experiences of HBV-related stigma were highly pervasive, with widespread impact on HRQoL. To address the burden of stigma, reducing internalized stigma would be most impactful as this was the most common and bothersome.

Indexed as

Cost of IllnessHepatitis B, ChronicSocial StigmaAdultAgedChinaFemaleHumansInterviews as TopicMaleMiddle AgedPolandQualitative ResearchQuality of LifeUnited StatesYoung Adulthepatitis B viruspsychological well‐beingqualitative researchquality of lifesocial stigma

Identifiers

PMID42499137
PMCPMC13400884

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.