Evidence map›Paper›PMID 42498732›Full record

ArticleOncogene2026

Autocrine CysLT

Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Venkatesh Katari, Somayeh Darzi, Srinivas Vinod Saladi, Ivana de la Serna, Charles K Thodeti, Sailaja Paruchuri

Abstract read
In one paragraph

Article in Oncogene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emma Elizabeth Sabu KattumanDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Lakshminarayan Reddy TeegalaDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.ORCID http://orcid.org/0000-0001-7725-8294
Venkatesh KatariDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Somayeh DarziDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Srinivas Vinod SaladiDepartment of Cell and Cancer Biology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.ORCID http://orcid.org/0000-0001-8147-4379
Ivana de la SernaDepartment of Cell and Cancer Biology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Charles K ThodetiDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Sailaja ParuchuriDepartment of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA. Sailaja.Paruchuri@UToledo.edu.ORCID http://orcid.org/0000-0003-2377-4327

Funding

Integration of Leukotriene and Prostaglandin Receptor Signaling in Mast Cell Activation and Pulmonary Inflammation during AsthmaR01AI144115 · NIAID · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI PARUCHURI, SAILAJA · 2019 to 2023
$1.8M
Novel cysteinyl leukotriene receptor signaling in regulating cellular, and molecular events in lung inflammationR01HL178459 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI Sailaja Paruchuri · 2025 to 2026
$1.1M
American Heart Association (American Heart Association, Inc.) 25PRE1373953American Heart Association (American Heart Association, Inc.) 25TPA1473648American Heart Association (American Heart Association, Inc.) AHA-TPA-971237NHLBI NIH HHS R01 HL178459NIAID NIH HHS R01 AI144115U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL178459U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 AI144115
6 · The paper itself

Abstract

Cutaneous melanoma remains the most lethal skin cancer due to profound tumor heterogeneity and the frequent development of resistance to current therapies. Here, we identify the cysteinyl leukotriene receptor 1 (CysLT

Indexed as

Adaptor Proteins, Signal TransducingMelanomaReceptors, LeukotrieneSkin NeoplasmsTranscription FactorsAnimalsAutocrine CommunicationCell Line, TumorCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHumansMAP Kinase Signaling SystemMiceSignal TransductionYAP-Signaling ProteinsAdaptor Proteins, Signal Transducingleukotriene D4 receptorReceptors, LeukotrieneTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID42498732
PMCPMC13503276

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.