ArticleCell2026
Dynamic dimer-of-dimers architecture defines Mg
Zhiyong Bai, X Edward Zhou, Wei Lü, Juan Du
Abstract read
In one paragraphArticle in Cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
4 authors.
Zhiyong BaiDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
X Edward ZhouDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Wei LüDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA; Department of Pharmacology, Northwestern University, Chicago, IL 60611, USA; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA. Electronic address: wei.lu@northwestern.edu.
Juan DuDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA; Department of Pharmacology, Northwestern University, Chicago, IL 60611, USA; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA. Electronic address: juan.du@northwestern.edu.
Funding
Structural and Functional Studies of the TRPM4 and TRPM5 ChannelsR01HL153219 · NHLBI · VAN ANDEL RESEARCH INSTITUTE · PI Wei Lu · 2020 to 2026
$3.9MStructural Basis of Nociceptor Channel TRPM3 gating and pharmacologyR01NS129804 · NINDS · VAN ANDEL RESEARCH INSTITUTE · PI Juan Du · 2023 to 2026
$2.8MElucidating structures and molecular mechanisms of Pannexin channelsR35GM138321 · NIGMS · VAN ANDEL RESEARCH INSTITUTE · PI LU, WEI · 2020 to 2024
$2.3MMolecular Mechanism of Magnesium Transport in Neuronal HomeostasisR01NS149623 · NINDS · NORTHWESTERN UNIVERSITY · PI Juan Du, Wei Lu · 2026 to 2026
$631kNHLBI NIH HHS R01 HL153219NIGMS NIH HHS R35 GM138321NINDS NIH HHS R01 NS129804NINDS NIH HHS R01 NS149623
6 · The paper itselfAbstract
Indexed as
Cation Transport ProteinsMagnesiumAdenosine TriphosphateBinding SitesBiological TransportCell MembraneCryoelectron MicroscopyHumansModels, MolecularProtein MultimerizationAdenosine TriphosphateCation Transport ProteinsCNNM4 protein, humanMagnesiumATP bindingCNNM4cryo-EM structuredimer of asymmetric dimersdomain swappinghumanmagnesium bindingmagnesium homeostasismagnesium sensingmagnesium transport
Identifiers
PMID42497866
PMCPMC13479726
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