Evidence map›Paper›PMID 42497305›Full record

ArticleHealth policy and planning2026

Catastrophic costs and impoverishment among tuberculosis-affected households in Nepal: results from a national patient cost survey.

Prajowl Shrestha, Naveen Prakash Shah, Sharad Kumar Sharma, Lok Raj Joshi, Ashish Lal Shrestha, Padmanav Ghimire, Basundhara Sharma, Rajendra Basnet, Ratna Bahadur Bhattarai, Sandesh Neupane and 6 more

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Article in Health policy and planning, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Prajowl ShresthaNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Naveen Prakash ShahNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Sharad Kumar SharmaNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Lok Raj JoshiInternational Union Against Tuberculosis and Lung Disease (The Union), Kathmandu, Nepal.
Ashish Lal ShresthaSave the Children, Kathmandu, Nepal.
Padmanav GhimireNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Basundhara SharmaNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Rajendra BasnetSave the Children, Kathmandu, Nepal.
Ratna Bahadur BhattaraiSave the Children, Kathmandu, Nepal.
Sandesh NeupanePublic Health Professional, Kathmandu, Nepal.
Rabin GautamWorld Health Organization (WHO), Kathmandu, Nepal.
Prasant Vikram ShahiWorld Health Organization (WHO), Kathmandu, Nepal.ORCID 0000-0003-0965-4652
Barsha ThapaWorld Health Organization (WHO), Kathmandu, Nepal.
Kenza BennaniWorld Health Organization (WHO), Kathmandu, Nepal.
Bir Bahadur RawalNational Tuberculosis Control Center, Ministry of Health and Food Safety, Thimi, Bhaktapur, Nepal.
Keshab DeubaPublic Health and Environment Research Center (PERC), Lalitpur, Nepal.ORCID 0000-0002-9933-2210

Funding

Global Fund to Fight AIDS, Tuberculosis and Malaria
6 · The paper itself

Abstract

Tuberculosis (TB) poses a significant economic burden on affected households. Despite the provision of free diagnosis and treatment services, patients and their households experience substantial financial hardship. This study aimed to estimate the catastrophic costs faced by TB patients in Nepal and identify associated factors. We conducted the first national cross-sectional survey of 1000 patients enrolled within the National Tuberculosis Program (NTP). The sample consisted of 600 drug-susceptible (DS-TB) and 400 drug-resistant TB (DR-TB) patients. Data were collected through structured interviews using the standardized TB patient cost survey questionnaire. Costs were categorized as direct medical, direct nonmedical, and indirect. Indirect costs were estimated using the human-capital approach. Catastrophic total costs due to TB were defined as total TB-related costs exceeding 20% of annual pre-TB household income. The mean age of participants was 43 years, and 65% were male. Forty-two percent of participants engaged in informal paid work and 70% had not completed secondary education. One-third of the participants reported having some form of social protection, with just 11% possessing health insurance coverage. Overall, 51% of TB-affected households faced catastrophic costs due to TB, with a higher proportion among DR-TB patients (76%) compared with DS-TB patients (51%). The financial burden was primarily driven by direct nonmedical costs (44%) and indirect costs (39%), substantially exceeding direct medical costs (17%). Factors associated with catastrophic total costs included belonging to a poorer wealth quintile, a DR-TB diagnosis, being the primary income earner, and lacking health insurance coverage. TB-related costs pushed 13% of households below the poverty line, increasing to 31% among DR-TB households. Mitigating this burden requires an integrated approach that aligns early diagnostic interventions with comprehensive social protection. Specifically, combining direct cash transfers for wage replacement with in-kind nutritional support is critical to protect high-risk households and reduce nonmedical financial shocks.

Indexed as

Catastrophic IllnessCost of IllnessHealth ExpendituresPovertyTuberculosisAdolescentAdultCross-Sectional StudiesFamily CharacteristicsFemaleHumansMaleMiddle AgedNepalSurveys and QuestionnairesYoung Adultcatastrophic costsimpoverishmentNepalpatient cost surveysocial protectiontuberculosis

Identifiers

PMID42497305
PMCPMC13586624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.