Evidence map›Paper›PMID 42497289›Full record

ArticleEuropean stroke journal2026

CATalyze-AI: accelerating referral for thrombectomy in acute stroke patients using an AI-based software. A prospective, multicentre, quasi-experimental cohort study.

Marta Olive-Gadea, Federica Rizzo, Dolores Cocho, Judit Roca Font, Marc Rodrigo-Gisbert, Marian Muchada, Marta Rubiera Del Fueyo, David Rodriguez-Luna, Renato Simonetti, Noelia Rodriguez-Villatoro and 17 more

Abstract readMulticenter Study
In one paragraph

Article in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Marta Olive-GadeaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-4637-1598
Federica RizzoStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Dolores CochoNeurology Department, Hospital General de Granollers, Granollers, Spain.
Judit Roca FontEmergency Department, Hospital Universitari de Vic, Vic, Spain.
Marc Rodrigo-GisbertStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marian MuchadaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marta Rubiera Del FueyoStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0001-8100-9477
David Rodriguez-LunaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0001-8053-4536
Renato SimonettiStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Noelia Rodriguez-VillatoroStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Jorge PagolaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Artur IzquierdoNeurology Department, Hospital General de Granollers, Granollers, Spain.
Gemma PlanellsEmergency Department, Hospital General de Granollers, Granollers, Spain.
Maria Jose CortesRadiology Department, Hospital Universitari de Vic, Vic, Spain.
Maria Àngels FontNeurology Department, Hospital Universitari de Vic, Vic, Spain.
Nicoletta BrunelliStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Adriano BonuraStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Manuel RequenaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Jordi MayolStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Ane MurilloStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Teresa Jordà-BaleriStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Judith CendreroGrup de Recerca en Ictus, Vall d'Hebron Institut de Recerca, Barcelona, Spain.
Alejandro TomaselloEmergency Department, Hospital Universitari de Vic, Vic, Spain.
Carlos MolinaStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Xabi UrraStroke Unit, Neurology Department, Hospital Clinic, Barcelona, Spain.
Alvaro Garcia-TornelStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marc RiboStroke Unit, Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.

Funding

Instituto de Salud Carlos III CM23/00280Instituto de Salud Carlos III JR22/00046
6 · The paper itself

Abstract

introductionTimely transfer of patients with suspected LVO remains critical in acute stroke systems. Artificial intelligence (AI)-based imaging tools are increasingly implemented to support triage in non-thrombectomy centres. We assessed whether integrating an AI algorithm within established tele-stroke centres reduces time to transfer decision. PATIENTS AND

methodsWe conducted a prospective, multicentre, quasi-experimental study comparing consecutive cohorts in 2 tele-stroke centres referring to a single comprehensive stroke centre, before and after implementation of the Methinks Stroke Suite, an AI algorithm for LVO detection on non-contrast CT (NCCT) and CTA. Consecutive transferred patients with suspected acute ischaemic stroke were included. Remote vascular neurologists retained responsibility for final transfer decisions. Each phase spanned approximately 15 months. The primary outcome was time from arrival at the local centre to emergency medical services activation. Secondary outcomes included workflow intervals, imaging utilisation and algorithm performance.

resultsWe included 265 patients (136 in the post-implementation cohort; 129 in the pre-implementation cohort). Adjusted median time from arrival to transfer request did not differ (median difference - 2.40 min; 95% CI, -6.16 to 4.48). Post-implementation, time from imaging to transfer request (-7.16 min; 95% CI, -13.02 to -1.85) and arrival to groin puncture (-31.28 min; 95% CI, -60.89 to -13.74) decreased. Computed tomography angiography acquisition at referring centres increased (28%-81%), reducing repeat imaging at the comprehensive centre (79%-42%). Non-contrast CT-based AI prediction yielded a positive predictive value of 66% for endovascular treatment.

conclusionArtificial intelligence implementation was not associated with a shorter time to transfer decision. Fewer redundant imaging examinations were associated with a shorter time to reperfusion.

Indexed as

Artificial IntelligenceIschemic StrokeReferral and ConsultationSoftwareStrokeThrombectomyAgedAged, 80 and overAlgorithmsFemaleHumansMaleMiddle AgedPatient TransferProspective StudiesTime-to-Treatmentartificial intelligenceLVOstroke

Identifiers

PMID42497289
PMCPMC13458394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.