Evidence map›Paper›PMID 42497157›Full record

ArticleThe neurologist2026

ZJUSXH Model: A Multilayer Model for Predicting 90-Day Neurological Outcome After Endovascular Thrombectomy in Acute Large Vessel Occlusion Stroke.

Jianli Wang, Feng Yang, Chengdong Sun, Chenglong Ye, Pan Li, Huan Tang, Guoliang Qian, Huaming Li, Zigang Yuan

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Article in The neurologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Jianli WangDepartment of Neurosurgery.
Feng YangDepartment of Neurology.
Chengdong SunDepartment of Neurosurgery, Shengzhou Traditional Chinese Medicine Hospital, Shengzhou, Zhejiang, China.
Chenglong YeSchool of Medicine, Shaoxing University, Shaoxing.
Pan LiSchool of Medicine, Shaoxing University, Shaoxing.
Huan TangDepartment of Neurology.
Guoliang QianInformation Centre.
Huaming LiDepartment of Thoracic Surgery, Zhejiang University Shaoxing Hospital.
Zigang YuanDepartment of Neurosurgery.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStroke is a leading cause of mortality and disability worldwide, particularly acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Although endovascular intervention has proven effective, individual outcomes vary considerably. This study aimed to identify key prognostic factors and develop a predictive model for neurological recovery in patients with LVO-AIS following endovascular thrombectomy (EVT).

methodsA total of 191 LVO-AIS patients who underwent EVT at the Neurosurgery Department of Zhejiang University Shaoxing Hospital from January 2022 to June 2023 were included in the analysis. Prognostic factors collected included demographic information, premorbid characteristics, initial laboratory data, neurological evaluation, and others. The 90‑day modified Rankin Scale (mRS) score served as the primary clinical outcome. A multilevel prognostic (MLP) model and an associated nomogram were developed to identify significant predictors and visualize their individual contributions to the outcome.

resultsThe Zhejiang University Shaoxing Hospital (ZJUSXH) model was developed, incorporating 11 key predictors: the National Institutes of Health Stroke Scale (NIHSS) score, symptom onset‑to‑recanalization (OTR) time, fasting blood glucose (FBS), hemoglobin (HGB), serum albumin (ALB), symptomatic intracerebral hemorrhage (sICH), the Controlling Nutritional Status (CONUT) score, the prognostic nutritional index (PNI), swallowing function, and the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification. The overall predictive accuracy of the model was 86.2%.

conclusionThe NIHSS score and OTR time emerged as the most critical prognostic factors. FBS, HGB, ALB, sICH, swallowing function, and TOAST classification were also significant predictors. In addition, the CONUT score and PNI showed a significant association with neurological outcomes. Both the developed ZJUSXH model and its corresponding nomogram demonstrated high predictive accuracy.

Indexed as

Endovascular ProceduresIschemic StrokeStrokeThrombectomyAgedFemaleHumansMaleMiddle AgedNomogramsPrognosisTreatment Outcomeacute ischemic strokeclinical outcomesendovascular thrombectomylarge vessel occlusionmultilayer perceptronnomogram

Identifiers

PMID42497157
PMCPMC13541605

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