Evidence map›Paper›PMID 42496728›Full record

ReviewDie Ophthalmologie2026

[Migraine aura: differential diagnostics between ophthalmology and neurology].

Carl H Göbel, Axel Heinze, Katja Heinze-Kuhn, Anna Cirkel, Hartmut Göbel

Abstract readReviewEnglish Abstract
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In one paragraph

Review in Die Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carl H GöbelSchmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland. cg@schmerzklinik.de.
Axel HeinzeSchmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland.
Katja Heinze-KuhnSchmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland.
Anna CirkelSchmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland.
Hartmut GöbelSchmerzklinik Kiel, Migräne- und Kopfschmerzzentrum, Heikendorfer Weg 9-27, 24149, Kiel, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine aura is a common and diagnostically important phase of migraine. Approximately 25-35 % of individuals with migraine experience fully reversible focal neurological symptoms that typically develop gradually, spread over time, and occur in succession. Visual symptoms are the most common and include scintillating scotomas, fortification spectra, photopsias (flashes of light), and transient visual field defects. Sensory, language, motor, and brainstem symptoms may also occur. This article reviews the clinical spectrum of migraine aura based on the ICHD-3 diagnostic criteria and its characteristic temporal evolution. Particular emphasis is placed on the recognition of isolated aura without subsequent headache. The gradual onset, progressive spread, and complete resolution of symptoms within 5-60 minutes are key features for the differential diagnosis. Migraine aura should be distinguished from transient ischemic attacks, epileptic phenomena, and retinal disorders. The article also presents migraine aura simulations as a useful tool to support clinical history-taking and patient education.

Indexed as

Migraine with AuraNeurologyOphthalmologyDiagnosis, DifferentialDiagnostic Techniques, OphthalmologicalHumansCortical spreading depression (CSD)Fortification spectrumICHD-3Scintillating scotomaTransient ischemic attack (TIA)

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.