Evidence map›Paper›PMID 42496719›Full record

ArticleWorld journal of urology2026

Does an emphasis on urinary continence compromise oncological outcomes after robot-assisted radical prostatectomy?

Kazuhiro Matsumoto, Keishiro Fukumoto, Yota Yasumizu, Nobuyuki Tanaka, Toshikazu Takeda, Hiroshi Asanuma

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Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Kazuhiro MatsumotoDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan. kazz_matsumoto@yahoo.co.jp.
Keishiro FukumotoDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
Yota YasumizuDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
Nobuyuki TanakaDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
Toshikazu TakedaDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
Hiroshi AsanumaDepartment of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn robot-assisted radical prostatectomy (RARP), surgical techniques aimed at preserving urinary continence-such as bladder neck preservation, nerve sparing, and dorsal venous complex (DVC) preservation-are increasingly adopted to improve postoperative quality of life. However, whether an excessive emphasis on functional preservation compromises oncological outcomes remains unclear.

methodsWe retrospectively analyzed 235 consecutive patients who underwent RARP performed by a single experienced surgeon. Patients were stratified according to (1) extent of bladder neck preservation (< 8 mm, 8-16 mm, > 16 mm), (2) nerve-sparing status (bilateral, unilateral, none), and (3) degree of DVC preservation (long, standard, short). Urinary continence at 3 months postoperatively (≤ 1 safety pad/day), positive surgical margin (PSM) rates, and biochemical recurrence (BCR) were evaluated.

resultsBladder neck preservation was associated with improved early continence recovery without increasing PSM or BCR rates. Bilateral nerve sparing resulted in superior continence outcomes; higher PSM rates in the non-nerve-sparing group reflected a more advanced pathological stage. DVC preservation showed the strongest association with continence recovery; however, aggressive DVC preservation was associated with a significantly higher PSM rate, predominantly at the apical and anterior regions. No significant differences in BCR were observed among groups.

conclusionsBladder neck preservation and nerve sparing can improve urinary continence without compromising oncological outcomes when appropriately applied. In contrast, aggressive DVC preservation may increase the risk of positive surgical margins and should be performed cautiously with careful patient selection.

Indexed as

Organ Sparing TreatmentsPostoperative ComplicationsProstatectomyProstatic NeoplasmsRobotic Surgical ProceduresUrinary IncontinenceAgedHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeUrinary BladderBladder neck preservationDVCIncontinenceNerve sparingRARPSurgical margin

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.