Evidence map›Paper›PMID 42496666›Full record

ArticleBasic & clinical pharmacology & toxicology2026

Technology-Driven Decision Support for Opioid Tapering: A Scoping Review.

Laurits Valberg Hemmingsen, Lærke Karner Overgaard, Uffe Kock Wiil, Daniel Pilsgaard Henriksen

Abstract readScoping Review
In one paragraph

Article in Basic & clinical pharmacology & toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurits Valberg HemmingsenSDU Health Informatics and Technology, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark.
Lærke Karner OvergaardDepartment of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0009-0001-8493-9415
Uffe Kock WiilSDU Health Informatics and Technology, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark.
Daniel Pilsgaard HenriksenDepartment of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneral practitioners manage most opioid tapering. This process requires time-consuming, individualised planning accounting for patient preferences, dose options and costs. Consequently, clinicians need tools to support tapering. This review explores existing international digital decision support systems for opioid tapering.

methodsWe conducted a scoping review following the JBI methodology. Five databases (PubMed, Embase, CINAHL, Cochrane and Web of Science) were searched in January 2026. Title/abstract and full-text screening were performed independently by two reviewers based on predefined eligibility criteria. Disagreements were resolved by a third reviewer. Data were extracted and summarised both descriptively and narratively.

resultsThe search identified 2340 studies, of which four met the eligibility criteria. The studies included described four different technology-driven decision support tools for opioid tapering. The tools varied in format and clinical context (primary and secondary care), but they all aimed to support clinicians in planning and managing opioid tapering. Evidence on clinical effectiveness and real-world implementation was limited across the studies.

conclusionOnly few studies have investigated technology-driven decision support for opioid tapering, and only one is set within a European context. While tools exist in different formats and clinical settings, evidence on their effectiveness and real-world implementation remains limited, highlighting a need for further development and evaluation.

Indexed as

Analgesics, OpioidDecision Support Systems, ClinicalDecision Support TechniquesHumansAnalgesics, Opioiddecision support toolopioid deprescribingopioid taperingscoping review

Identifiers

PMID42496666
PMCPMC13398398

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.