Evidence map›Paper›PMID 42496565›Full record

ReviewBiotech (Basel (Switzerland))2026

Current Characterization Techniques Applied to Microalgae-Fungal Pellets: Unraveling the Mechanisms of Adhesion and Stability Focused on Nutrient Recovery/Recycling and Bioprocess Diversification.

João Victor Oliveira Nascimento da Silva, Carlos Eduardo de Farias Silva, Tomás Agustín Rearte, Eleni Kougia, Giorgos Markou, Albanise Enide da Silva

Abstract readReview
In one paragraph

Review in Biotech (Basel (Switzerland)), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João Victor Oliveira Nascimento da SilvaTechnology Center, Federal University of Alagoas, Maceió 57072-970, Brazil.ORCID 0000-0002-1787-1107
Carlos Eduardo de Farias SilvaTechnology Center, Federal University of Alagoas, Maceió 57072-970, Brazil.ORCID 0000-0002-1462-1145
Tomás Agustín RearteCátedra de Química Inorgánica y Analítica, Facultad de Agronomía, Universidad de Buenos Aires, Buenos Aires C1417DSE, Argentina.ORCID 0000-0003-0690-7191
Eleni KougiaInstitute of Technology of Agricultural Products, ELGO-Dimitra, 14123 Athens, Greece.
Giorgos MarkouInstitute of Technology of Agricultural Products, ELGO-Dimitra, 14123 Athens, Greece.ORCID 0000-0002-2507-9080
Albanise Enide da SilvaTechnology Center, Federal University of Alagoas, Maceió 57072-970, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 312996/2022-5, 404455/2024-7, 440026/2024-5 and 445932/2024-4Governo do Estado de Alagoas E:60030.0000002360/ 2022, E:60030.0000000318/2023 and E:60030.0000001407/2025
6 · The paper itself

Abstract

Microalgae-fungal pellets have been studied as a versatile and robust biotechnological platform, offering significant advantages for microalgal biomass harvesting, wastewater treatment, biofuels production and/or obtaining of value-added products. This review presents an integrated analysis of the mechanisms governing the formation, stability, and functionality of these systems, combining physicochemical, biological, and mathematical modelling approaches and aims to describe the current state of the art and main research needs. The aggregation process is strongly influenced by the complementarity of the surface properties of microalgae and filamentous fungi, including electrostatic interactions, production of extracellular polymeric substances (EPSs), and modifications in surface roughness. Recent advances in multiscale characterization techniques, such as confocal microscopy, micro-computed tomography, atomic force microscopy, and X-ray photoelectron spectroscopy, have allowed a more precise elucidation of the internal architecture and surface chemistry of the pellets. In parallel, biological characterization through enzymatic assays, oxidative stress biomarkers, and photosynthetic activity analyses has provided relevant information on the metabolic responses and functional resilience of the consortium. Additionally, the incorporation of mathematical flocculation models can contribute to the prediction of pellet growth, density, and stability, supporting process optimization and application. The understanding of these interaction phenomena is important for the design of high-yield and efficient systems, including their development and validation, to expand the use of microalgae-fungal pellets in bioprocesses, as evidenced by this review.

Indexed as

co-aggregationfilamentous fungusmicroalgamicroalgae–fungal cultivationmicroalgae-fungimicroalga–fungusmicroalga-fungus consortium

Identifiers

PMID42496565
PMCPMC13397844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.