Evidence map›Paper›PMID 42496539›Full record

ArticleEpidemiologia (Basel, Switzerland)2026

Determinants of Medication Storage and Disposal Practices in Brazil: A Cross-Sectional Study with Implications for Environmental Exposure.

Jorge Fernando Carrozza, Clovis Bergamin Griso, Rafaela Felix Vieira Bastos, Gabriel Leandro Jesus Santos, Marcela Cristina Garnica-Siqueira, Gabriela Moraes Oliveira, Thiago José Dionísio, Carlos Ferreira Santos, Adriana Maria Calvo

Abstract read
In one paragraph

Article in Epidemiologia (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jorge Fernando CarrozzaDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.
Clovis Bergamin GrisoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0009-0008-9208-9562
Rafaela Felix Vieira BastosBauru School of Medicine, University of São Paulo, Bauru 17012-901, SP, Brazil.
Gabriel Leandro Jesus SantosDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.
Marcela Cristina Garnica-SiqueiraBauru School of Medicine, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-7471-7093
Gabriela Moraes OliveiraDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-0990-7106
Thiago José DionísioDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-1655-4425
Carlos Ferreira SantosDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-0405-3500
Adriana Maria CalvoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, SP, Brazil.ORCID 0000-0002-2876-0955

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

BACKGROUND/

objectivesInappropriate medication storage and disposal are recognized public health concerns and represent a relevant source of environmental exposure to pharmaceutical compounds, with potential implications for ecosystem and human health. Identifying population-level determinants of these behaviors is essential to support targeted interventions and risk mitigation strategies.

methodsA cross-sectional population-based study was conducted using a structured survey administered to Brazilian adults. The questionnaire assessed medication storage practices, disposal behaviors, and prior exposure to guidance on appropriate medication handling. Descriptive statistics were used to characterize the sample, and multivariate logistic regression analysis was performed to identify independent predictors of appropriate disposal practices.

resultsA total of 475 participants were included in the analysis. Although awareness of the environmental impact of improper medication disposal was high, inappropriate practices remained prevalent. Multivariate logistic regression identified educational level as the primary independent determinant of appropriate disposal practices (

conclusionsThe findings highlight a gap between awareness and practice and identify key sociodemographic determinants influencing medication disposal behaviors. From an environmental epidemiology perspective, improper disposal may contribute to the dissemination of pharmaceutical residues in water systems, representing an indirect but widespread exposure pathway. Targeted public health strategies focusing on high-risk groups are needed to promote safe medication handling and reduce environmental and health risks.

Indexed as

environmental pollutionenvironmental sustainabilityhealthcare wastemedication disposalmedication storagepharmaceuticalspublic awareness

Identifiers

PMID42496539
PMCPMC13397877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.