ArticleMuscles (Basel, Switzerland)2026
Histomorphological Effects of Repeated Administration of the TRPA1 Antagonist HC-030031 on Intrafusal and Extrafusal Muscle Fibers in Healthy Young Rats.
Article in Muscles (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel expressed in primary sensory neurons and has been proposed as a therapeutic target for pain management. However, the effects of repeated administration of a TRPA1 antagonist on peripheral tissue morphology remain unclear. This study examined whether repeated HC-030031 administration affected the histomorphology of skeletal muscle fibers and muscle spindles in rats. Male Fischer 344 rats were assigned to a control group (Con,
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