Evidence map›Paper›PMID 42496318›Full record

ArticleJournal of xenobiotics2026

A SAR-Based Classification Model for Assessing Pesticide Toxicity to

Nadia Iovine, Anna Lombardo, Alessandra Roncaglioni, Emilio Benfenati

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nadia IovineDepartment of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy.ORCID 0009-0008-1076-4385
Anna LombardoDepartment of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy.ORCID 0000-0002-8364-4797
Alessandra RoncaglioniDepartment of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy.
Emilio BenfenatiDepartment of Environmental Health Science, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milano, Italy.ORCID 0000-0002-3976-5989

Funding

European Food Safety Authority OC/EFSA/IDATA/2022/02
6 · The paper itself

Abstract

Pollinators are essential for maintaining ecosystem stability and agricultural productivity, yet their populations are in decline due to various stressors, including parasites, pathogens, climate change and pesticide exposure. Protecting pollinators has become a priority for environmental safety and food security. Regulatory authorities, including the European Food Safety Authority (EFSA), the Environmental Protection Agency (EPA) and the Organisation for Economic Co-operation and Development (OECD), have guidelines for pesticide risk assessment, but conventional testing methods are costly and time-consuming, limiting their applicability to large chemical datasets. Computational approaches, such as Structure-Activity Relationship (SAR) models, offer efficient alternatives by enabling the rapid screening of pesticides for potential toxicity to pollinators. In this study, we used a dataset of 357 compounds to develop a classification model based on structural alerts to predict oral acute toxicity in

Indexed as

classification modelenvironmental toxicologyhoney beesLD50SARSARpy

Identifiers

PMID42496318
PMCPMC13398046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.