ArticleJournal of xenobiotics2026
Pregnancy Exposure to Polycyclic Aromatic Hydrocarbons (PAHs): Exploratory Comparative Levels in Blood Serum Samples from Different Regions in Antioquia, Colombia.
Article in Journal of xenobiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Maternal exposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy has been associated with adverse obstetric and perinatal outcomes, including miscarriage, low birth weight, intrauterine growth restriction, and spontaneous abortion. Exposure occurs through multiple pathways, including dietary intake and inhalation, which ultimately determine the final body burden. PAHs may reach relevant levels in the blood, representing the initial step in their internal distribution to the placenta, umbilical cord, and breast milk, thereby compromising maternal-fetal health. In this exploratory study, maternal blood samples were collected from pregnant women residing in different regions of Antioquia, Colombia. Serum was isolated from whole blood, subsequently extracted using freezing-assisted liquid-liquid extraction, purified by solid-phase extraction, and analyzed by GC-MS. Method performance showed PAH recoveries between 60 and 120%, limits of detection (LOD) ranging from 0.5 to 3.3 ng·mL
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