Evidence map›Paper›PMID 42496235›Full record

ArticleDermatopathology (Basel, Switzerland)2026

Diagnosis of Syphilis in Paraffin-Embedded Skin Biopsies: Comparison of

Charlotte C Fuchs, Bastian Stoffers, Stephan A Braun, Almut Böer-Auer

Abstract read
In one paragraph

Article in Dermatopathology (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Charlotte C FuchsDepartment of Dermatology, University Hospital Münster, Von-Esmarch-Straße 58, 48149 Münster, Germany.ORCID 0009-0001-1644-9297
Bastian StoffersDermatologikum Hamburg, Stephansplatz 5, 20354 Hamburg, Germany.ORCID 0000-0003-2401-4338
Stephan A BraunDepartment of Dermatology, University Hospital Münster, Von-Esmarch-Straße 58, 48149 Münster, Germany.ORCID 0000-0002-5600-0195
Almut Böer-AuerDepartment of Dermatology, University Hospital Münster, Von-Esmarch-Straße 58, 48149 Münster, Germany.ORCID 0000-0001-7928-8569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis remains one of the most prevalent sexually transmitted infections. Serology is the diagnostic gold standard, but skin biopsies aid in ambiguous cases. Treponemas can be detected in tissue by immunohistochemistry (IHC) and polymerase chain reaction (PCR); however, their comparative performance across disease stages has not been extensively studied. This retrospective study of 48 formalin-fixed, paraffin-embedded (FFPE) skin biopsies from syphilis cases compared

Indexed as

CD 138immunohistochemistryPCRplasma cellssyphilisTreponema pallidum

Identifiers

PMID42496235
PMCPMC13398093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.