ArticleProceedings (Baylor University. Medical Center)2026
The urological burden of lichen sclerosis: implications for multidisciplinary surveillance and management.
Article in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
backgroundLichen sclerosis (LS) is a chronic inflammatory condition predominantly affecting the anogenital skin, with genitourinary involvement leading to scarring, phimosis, and voiding dysfunction. The long-term urological sequelae, including urological interventions, remain unexplored in large cohorts.
methodsUsing the TriNetX database, a retrospective propensity score-matched cohort analysis was conducted, comparing 36,974 patients with LS to 36,974 controls matched by demographics, diabetes mellitus, tobacco use, recurrent urinary tract infections, immunosuppressant use, and prior cystourethroscopy and/or temporary indwelling bladder catheter. Outcomes involved patients with >12 months follow-up with urological complications or urological interventions, identified through ICD-10 codes.
resultsOverall, urethral strictures (relative risk [RR]: 2.256; 95% confidence interval [CI]: 1.753-2.905;
conclusionsThese findings highlight the multisystematic involvement of LS and emphasize the importance for comprehensive dermatologic and urologic follow-up.
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