Evidence map›Paper›PMID 42496156›Full record

ArticleMicrobiology spectrum2026

Single-cell transcriptomics reveal PD-1-loss-driven immune dysregulation of pulmonary lymphocytes during early

Bing Yang, Haoqi Wang, Siqi Zhang, Jinru Cai, Gang Cao, Xuan Ma, Jinxia Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bing YangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.ORCID 0000-0002-1183-3708
Haoqi WangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Siqi ZhangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.
Jinru CaiCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Gang CaoFaculty of Life and Health Sciences, Shenzhen University of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Xuan MaCollege of Agriculture, Ningxia University, Yinchuan, China.ORCID 0000-0003-3790-8912
Jinxia DaiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China.ORCID 0000-0001-7060-5185

Funding

National Natural Science Foundation of China 82272416, U21A20259
6 · The paper itself

Abstract

Although PD-1 blockade shows strong antitumor efficacy and is being considered for chronic infections including

Indexed as

LungLymphocytesMycobacterium tuberculosisProgrammed Cell Death 1 ReceptorTuberculosisAnimalsB-LymphocytesMiceMice, Inbred C57BLMice, KnockoutSingle-Cell AnalysisT-Cell ExhaustionT-Lymphocytes, RegulatoryTranscriptomePdcd1 protein, mouseProgrammed Cell Death 1 Receptorcellular communicationMycobacterium tuberculosisprogrammed cell death receptor 1pulmonary lymphocytestranscriptional regulatory networkstranscriptomic landscape

Identifiers

PMID42496156
PMCPMC13532292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.