Evidence map›Paper›PMID 42496129›Full record

ArticleMicrobiology spectrum2026

Differential virulence potential of different clades of multidrug-resistant

Nathalie Chen, Brooke P Dresden, Margaret Cassady, Marissa P Griffith, Lora L Pless, Lee H Harrison, Ryan K Shields, John F Alcorn, Daria Van Tyne

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nathalie ChenDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9951-5642
Brooke P DresdenDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Margaret CassadyDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Marissa P GriffithDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Lora L PlessDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0163-3689
Lee H HarrisonDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-3787-2705
Ryan K ShieldsDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9794-5665
John F AlcornDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5997-7711
Daria Van TyneDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7284-0103

Funding

Enhanced Detection System for Healthcare-Associated Transmission of InfectionR01AI127472 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2016 to 2025
$7.6M
Influenza A Inhibits TH17 Host Defense Against Bacterial PneumoniaR01HL107380 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALCORN, JOHN F · 2012 to 2024
$5.4M
The Role of Staphylococcus aureus SasD in LungR01HL167449 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI John F Alcorn · 2023 to 2026
$2.1M
University of Pittsburgh Training Program in Antimicrobial ResistanceT32AI138954 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2019 to 2023
$971k
Complement resistance and acute lung injury during Klebsiella pneumoniae infectionF30HL178011 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, NATHALIE · 2025 to 2025
$54k
American Heart Association 25PRE1375562National Institute of Allergy and Infectious Diseases R01AI127472National Institute of Allergy and Infectious Diseases T32AI138954NHLBI NIH HHS F30 HL178011NHLBI NIH HHS F30HL178011NHLBI NIH HHS R01 HL107380NHLBI NIH HHS R01HL107380NHLBI NIH HHS R01 HL167449NHLBI NIH HHS R01HL167449NIAID NIH HHS R01 AI127472NIAID NIH HHS T32 AI138954
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeAnimalsAnti-Bacterial AgentsBacterial CapsulesFemaleHumansMiceMultilocus Sequence TypingVirulenceAnti-Bacterial Agentsantibiotic resistancecapsulecomplementKlebsiella pneumoniaeserum

Identifiers

PMID42496129
PMCPMC13532268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.