Evidence map›Paper›PMID 42496011›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Human Foetal Neuroblasts Exhibit BK Channel-Dependent Membrane Voltage Oscillations upon Depolarization.

Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese

Abstract read
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In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elisabetta CoppiDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-4434-5919
Federica CherchiDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0001-6742-456X
Martina VenturiniDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.
Federico TommasiDepartment of Physics and Astronomy, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0002-3178-2514
Sandro GonziDepartment of Physics and Astronomy, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-4754-645X
Chiara CapacciDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.
Giulia GuarnieriDepartment of Experimental and Clinical Medicine, Section of Human Anatomy and Histology, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0002-3056-7492
Pasquale GallinaDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.
Annamaria MorelliDepartment of Experimental and Clinical Medicine, Section of Human Anatomy and Histology, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0001-8027-9870
Anna Maria PuglieseDepartment of Neuroscience, Psychology, Division of Pharmacology and Toxicology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0001-7554-5740

Funding

Supported by FISM - Fondazione Italiana Sclerosi Multipla - cod. 2024/R-Single/038 and financed or co-financed with the '5per mille' public foundingUniversity of Florence RICATEN-2025
6 · The paper itself

Abstract

Immature neurobalsts might present peculiar electrical activities before developing standard neuronal-like excitability. We previously described electrophysiological properties of primary neuroblast cultures isolated from the nucleus basalis of Meynert (hfNBMNs) of 12-week human foetuses, which possess the machinery for acetylcholine (ACh) synthesis, degradation and transport, functional muscarinic and nicotinic ACh receptors and tetrodotoxin- (TTX-) sensitive Na

Indexed as

Ca2+‐activated K+ channelshuman foetal neurblastsintracellular Ca2+ risemembrane voltagenucleus basalis of Meynertoscillation

Identifiers

PMID42496011
PMCPMC13397815

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.